Antibody Targets Library

Design antibodies against any validated therapeutic target.

From immune checkpoints and cytokines to viral antigens and amyloids, our in silico platform supports the design of monoclonal antibodies, bispecifics and nanobodies against structurally characterized targets - with a focus on candidates ready to move towards the clinic.

3,800+
Antibodies in database
45
Validated targets
1,200+
Affinity measurements
70+
Curated sources
Antibody Targets Library

Explore all engineered targets

Each target page provides in-depth scientific analysis, engineering approach, clinical landscape, and the MAbSilico database profile. Click any card to explore.

From targets to Phase-I-ready assets

Our 6-step workflow runs on top of every target in this library.

1
Target characterization
Structural analysis, epitope mapping, IP landscape.
2
Epitope & format
mAb, bispecific, nanobody. Strategy-driven.
3
Region selection
Most relevant binding regions.
4
Candidate identification
Library screen + in silico generation.
5
Multiparametric optimization
Affinity · developability · Fc · bio-better · PI-friendly.
6
Selection & transfer
Ready-to-clone sequences for your CRO / internal team.
Anne Poupon, MAbSilico co-founder, working with antibody design software

Don't see your target ?

Our platform handles any target with an available 3D model. Tell us about your project and we’ll come back with a feasibility note.

Contact us