Antibody Targets Library

Design antibodies against any validated therapeutic target.

From immune checkpoints to cytokines, viral antigens to amyloids — our in silico platform engineers monoclonals, bispecifics and nanobodies on any target with a 3D model. Phase-I-ready assets, not just binders.

3D Structure Visualization
Antibody · Target Complex
3,800+
Antibodies in database
45
Validated targets
1,200+
Affinity measurements
70+
Curated sources

Browse by therapeutic area

Our platform is not confined to one therapeutic area. Each family leads to a structured set of targets, antibodies and case studies.

Family
Inflammation
8 targets · 640 antibodies
  • Cytokines / chemokines
  • Receptors
  • Enzymes
Family
Infectious
6 targets · 380 antibodies
  • Viral proteins
  • Bacterial antigens
Family
Neurology
4 targets · 210 antibodies
  • Amyloids
  • Receptors
Family
Metabolism
5 targets · 180 antibodies
  • Hormones
  • Metabolic receptors
Family
Fibrosis
3 targets · 130 antibodies
  • Growth factors
  • ECM targets

Immuno-oncology · By mechanism

Six high-priority target classes, 15 targets engineered on the platform.

Featured
CTLA-4
Cytotoxic T-lymphocyte antigen 4 · UniProt P16410
1,147
Abs
450+
Affinities
22
INNs
PD-1 / PD-L1
Programmed cell death protein 1
892
Abs
312
Affinities
INNs
LAG-3
Lymphocyte activation gene 3
247
Abs
89
EC50
INNs
TIGIT
T-cell immunoreceptor with Ig and ITIM domains
178
Abs
62
Affinities
INNs
TIM-3
T-cell immunoglobulin mucin-3
156
Abs
54
Affinities
INNs
VISTA
V-domain Ig suppressor of T-cell activation
98
Abs
34
Affinities
INNs

From targets to Phase-I-ready assets

Our 6-step workflow runs on top of every target in this library.

01
Target characterization
Structural analysis, epitope mapping, IP landscape.
02
Epitope & format
mAb, bispecific, nanobody. Strategy-driven.
03
Region selection
Most relevant binding regions.
04
Candidate identification
Library screen + in silico generation.
05
Multiparametric optimization
Affinity · developability · Fc · bio-better · PI-friendly.
06
Selection & transfer
Ready-to-clone sequences for your CRO / internal team.

Don’t see your target?

Our platform handles any target with an available 3D model. Tell us about your project and we’ll come back with a feasibility note.

Antibody Targets Library

Explore all engineered targets

Each target page provides in-depth scientific analysis, engineering approach, clinical landscape, and the MAbSilico database profile. Click any card to explore.

Immune CheckpointsImmuno-oncology · 6 targets